

Because of the sparse vegetation, game viewing in Karoo National Park is easily facilitated. Best viewing is achieved on the 13km “Lammertjiesleegte” Route on the plains.
Large herbivores such as Red Hartebeest, Black Wildebeest, Eland, the two zebra species, kudu and springbok are all regularly seen. Klipspringer are regularly seen on the pass of the same name. Other species are less obvious due to smaller size, nocturnal habits or restriction to the wilderness areas of the park.
| Specie | Specie |
|---|---|
| Cape rock elephant-shrew | Cape Fox |
| Smith's rock elephant-shrew | Bat-eared Fox |
| Round-eared elephant-shrew | Cape Clawless Otter |
| Lesser red musk shrew | Striped Polecat |
| Forest shrew | Water Mongoose |
| Lesser dwarf shrew | Yellow Mongoose |
| Common split-faced bat |
Small Grey Mongoose |
| Cape serotine bat | Suricate |
| Melck's serotine bat |
Small-spotted Genet |
| Vervet monkey |
Aardwolf |
| Chacma Baboon |
Caracal |
| Cape Hare |
African Wildcat |
| Scrub Hare |
Antbear (Aardvark) |
| Smith’s Red Rock Rabbit | Rock Hyrax |
| Riverine Rabbit |
Black Rhinoceros |
| Pouched mouse | Cape Mountain Zebra |
| Grey pygmy climbing mouse |
Burchell’s Zebra (with Quagga bred characteristics) |
| Pygmy mouse |
Black Wildebeest |
| Short-tailed gerbil |
Red Hartebeest |
| Hairy-footed gerbil |
Springbok |
| Grant's rock mouse |
Klipspringer |
| Namaqua rock mouse |
Steenbok |
| Multimammate mouse |
Gemsbok |
| Striped mouse |
Kudu |
| Saunders' vlei rat |
Eland |
| Karoo bush rat |
Common Duiker |
| Spectacled Dormouse |
Gemsbok |
| Porcupine |
Grey Rhebuck |
| Common Molerat | Mountain reedbuck |
Karoo National Park has a very rich reptilian fauna. Of particular significance are the 5 species of tortoise. However there is also a terrapin, an agama, 2 chameleons, a monitor, 18 snakes and several geckos, skinks and lizards.
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